Julius Liobikas

Anthocyanins as substrates for mitochondrial complex I - protective effect against heart ischemic injury

Journal: 
Publication Year: 
2015
Authors: 

Skemiene K, Liobikas J, Borutaite V

Abstract: 

Anthocyanins, a subclass of flavonoids, are known to protect against myocardial ischemia, however, little is known about their direct, acute effects on mitochondria injured by the ischemic insult. In this study, the effects of delphinidin 3-O-glucoside (Dp3G), cyanidin 3-O-glucoside (Cy3G) and pelargonidin 3-O-glucoside (Pg3G) on the activity of complex I of the mitochondrial respiratory chain were studied in mitochondria isolated from normal and 45 min ischemia-damaged rat hearts.

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