C6 glioma cell culture; Ethanol; Extract of propolis; Mitochondrial respiration; Polyethylene glycol; Polyphenols; Radical scavenging activity; Superoxide; Water

Comparison of aqueous, polyethylene glycol-aqueous and ethanolic propolis extracts: antioxidant and mitochondria modulating properties.

Publication Year: 
2018
Authors: 

Kubiliene L, Jekabsone A, Zilius M, Trumbeckaite S, Simanaviciute D, Gerbutaviciene R, Majiene D

Abstract: 

Propolis is multicomponent substance collected by honeybees from various plants. It is known for numerous biological effects and is commonly used as ethanolic extract because most of active substances of propolis are ethanol-soluble. However, water-based propolis extracts could be applied more safely, as this solvent is more biocompatible. On the other hand, water extracts has significantly smaller range and quantity of active compounds. The extraction power of water could be enhanced by adding co-solvent which increases both solubility and penetration of propolis compounds.